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・ Interleaved memory
・ Interleaved polling with adaptive cycle time
・ Interleaving
・ Interleaving (disk storage)
・ Interlegis
・ Interlego AG v Tyco Industries Inc
・ Interlenghi
・ Interleukin
・ Interleukin 1 family
・ Interleukin 1 receptor antagonist
・ Interleukin 1 receptor, type I
・ Interleukin 1 receptor, type II
・ Interleukin 10
・ Interleukin 10 receptor, alpha subunit
・ Interleukin 10 receptor, beta subunit
Interleukin 11
・ Interleukin 11 receptor alpha subunit
・ Interleukin 12
・ Interleukin 12 receptor, beta 1 subunit
・ Interleukin 12 receptor, beta 2 subunit
・ Interleukin 12 subunit beta
・ Interleukin 13
・ Interleukin 13 receptor, alpha 1
・ Interleukin 15
・ Interleukin 15 receptor, alpha subunit
・ Interleukin 16
・ Interleukin 17
・ Interleukin 18
・ Interleukin 19
・ Interleukin 2


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Interleukin 11 : ウィキペディア英語版
Interleukin 11

Interleukin 11 (IL-11) is a protein that in humans is encoded by the ''IL11'' gene.〔
IL-11 is a multifunctional cytokine first isolated in 1990 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. It is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin.
The human IL-11 gene, consisting of 5 exons and 4 introns, is located on chromosome 19, and encodes a 23 kDa protein. IL-11 is a member of the IL-6-type cytokine family, distinguished based on their use of the common co-receptor gp130. Signal specificity is provided by the IL-11Rα subunit.
== Downstream signalling ==

Signal transduction is initiated upon binding of IL-11 to IL-11Ralpha and gp130, facilitating the homodimerization of gp130 molecules. This permits gp130-associated Janus kinases (JAK) to become activated and phosphorylate intracellular tyrosine residues on gp130.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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